Multi-Center Validation of the Trauma Specific Frailty Index in Geriatric Trauma Patients


Frailty is defined as a condition of reduced resistance to stressors due to a decline in physiological reserves, and it is a major health burden in the geriatric population. Multiple studies have shown that frailty is associated with adverse health outcomes such as in-hospital complications, readmissions, and adverse discharge disposition, as well as increased risk for mortality. Physicians at Banner University Medical Center in Arizona developed the Trauma Specific Frailty Index (TSFI), consisting of 15 variables that can reliably predict the presence of frailty and pre-frailty syndrome in geriatric trauma patients. The primary aim of this prospective validation study is to implement the TSFI at a multi-institutional level to test its predictive ability on a larger scale. The secondary aim of the study is to evaluate the association of frailty and morbidity, mortality, adverse discharge disposition, and post discharge follow up in a multicenter cohort of geriatric trauma patients. Essentia Health-St. Mary’s Medical Center Level I Trauma Center is one of the sites participating in this study. The study plans to enroll 1,500 subjects across all of the sites.

The Lead Principal Investigator is Dr. Bellal Joseph, Banner University Medical Center, University of Arizona. Dr. Kristin Colling is the Site Principal Investigator. Melissa Harry, PhD, is the Site Co-Investigator.

Research Study Categories


  • Trauma


Trauma Research Team, [email protected]


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