COG AALL1631: International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL) Testing Imatinib in Combination With Two Different Cytotoxic Chemotherapy Backbones

Objective

This randomized phase III trial studies how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagno
sed Philadelphia chromosome positive acute lymphoblastic leukemia. Imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving imatinib mesylate and combination chemotherapy may work better in treating patients with Philadelphia chromosome positive acute lymphoblastic leukemia.

https://clinicaltrials.gov/ct2/show/NCT03007147

Location: Essentia Health Cancer Centers

Research Study Categories

• Pediatric Studies

Specialty

• Hematology

Contact

Cancer Clinical Trials at 218-786-3308
or cancertrials@essentiahealth.org