Evaluation of a Protocol for Early Detection of Brain Hemorrhage Anticoagulation Correction in Head Injured Patients on Anticoagulants


Anticoagulant use is common to reduce the risk of stroke in individuals with cardiac disease and prothrombotic. Management of anticoagulation in trauma patients is important to prevent uncontrolled hemorrhage, as patients who suffer a traumatic intracranial hemorrhage and are on anticoagulants have a greater risk of mortality. The Traumatic Intracranial Hemorrhage (TICH) protocol was implemented at Essentia Health-St. Mary’s Medical Center (EH-SMMC) in March 2007 with the intent of providing expeditious care and early diagnosis of anticoagulated traumatic intracranial hemorrhage, and the rapid reversal of anticoagulants. The aim of this study is to evaluate the effectiveness of the TICH protocol for patients with a positive initial head CT scan by describing and comparing outcomes of patients treated during the pre- and post-TICH protocol implementation time periods. Outcomes to be assessed include mortality, length of stay, and head bleed.

Dr. Kristin Colling is the Principal Investigator. Melissa Harry, PhD, and Dr. Steven Eyer are Co-Investigators.

Principal Investigator(s)
Dr. Kristin Colling, MD

Research Study Categories

  • Adult Studies


  • Trauma
Trauma Research Team at
or traumaresearchteam@essentiahealth.org

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