ACTIV-6: A Clinical Research Study

ACTIV-6 is an at-home clinical study working to find safe treatments for COVID-19. The research study is testing medications that are approved for treating health conditions other than COVID-19 to see if they can help people with mild to moderate COVID-19 feel better faster and stay out of the hospital.

What is This Study About?

ACTIV-6 is a large clinical research study testing existing prescription and over-the-counter medications for adults with mild-to-moderate COVID-19 symptoms who are not sick enough to be hospitalized. The trial is funded by the National Institutes of Health (NIH).

People can participate from anywhere in the U.S, and medications are shipped at no cost. Participation involves taking the study medication and keeping track of your symptoms and how you feel over 90 days.

What Medications are Being Studied?

ACTIV-6 is studying the following medications prioritized by the National Institutes of Health. These medications have already been approved by the U.S. Food & Drug Administration for other conditions.

  • Fluticasone - an inhaled steroid commonly prescribed for asthma and chronic obstructive pulmonary disease
  • Fluvoxamine - a selective serotonin reuptake inhibitor (SSRI), often prescribed for depression
  • Ivermectin - used to treat parasitic infections

Who is Eligible?

You may be eligible if you:

  • Are at least 30 years old
  • Not in the hospital and tested positive for COVID-19 within the past 10 days
  • Have had at least two COVID-19 symptoms for 7 days or less

Why is ACTIV-6 Important?

Vaccines are available, but new, more transmissible variants of the virus are emerging in the U.S. People are still getting sick, and many remain at risk for the disease.

Results from ACTIV-6 will help researchers understand how existing medications can improve symptoms and limit hospitalizations for people with mild-to-moderate COVID-19.

How Can I Join?

If you're interested in joining the ACTIV-6 study or you'd like more information.

Call: 1-833-385-1880



Call Essentia Health: 218-576-0381

Join ACTIV-6

For more information or to join the ACTIV-6 study

Call Essentia Health:218-576-0381
Call Toll-Free: 1-833-383-1880

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